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The Centers for Disease Control and Prevention today released a describing the characteristics of multisystem inflammatory syndrome (MIS-C), a rare but serious condition that states have reported in more than 500 children with COVID-19.

According to the report, most MIS-C cases have features of shock, with cardiac involvement, gastrointestinal symptoms and significantly elevated markers of inflammation.

“As the COVID-19 pandemic continues, with the number of cases increasing in many jurisdictions, health care providers should continue to monitor patients to identify children with a hyperinflammatory syndrome with shock and cardiac involvement,” the authors said. “Suspected MIS-C patients should be reported to local and state health departments.”