Study: Convalescent plasma safe for patients with severe COVID-19
A study of the first 20,000 adults hospitalized with severe or life-threatening COVID-19 to receive convalescent plasma found the investigational therapy safe in this diverse group of patients, according to findings from the Food and Drug Administration鈥檚 Expanded Access Program for COVID-19 in Mayo Clinic Proceedings.
The mortality rate in the first seven days after transfusion was 8.6%, down from 12% in an earlier study of the first 5,000 patients, and serious adverse events remained low at less than 1%, the authors said.
鈥淕iven the accelerating deployment of this therapy, these emerging data provide early safety indicators of convalescent plasma for COVID-19 treatment and suggest research should shift focus from safety toward determining the efficacy of convalescent plasma,鈥 they said.