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Investments in digital health startups have whipsawed in recent years. After record-breaking investments in 2020 and 2021, sharp dips followed the next two years. For 2025, a rebound may be in store, according to a recent .

The survey, conducted in September, of 103 senior leaders whose companies sell digital health products, found that 81% have a positive outlook or are cautiously optimistic about investment prospects for this year. Nearly the same percentage (79%) said that their organizations will pursue new investment capital in the next 12 months.

And if digital health company funding rounds early this year are any indication, it could be a bounce-back year for startups. Here are some of the more significant digital health funding rounds announced in Q1, according to , which reports on the business of technology, startups and venture capital.

The biotech firm that focuses on cellular reprogramming, autophagy (the body’s process of reusing old and damaged cell parts) and plasma-inspired therapeutics designed to help people live longer raised a $1 billion round led by Italian financier Sandro Salsano. The capital will be used to back clinical trials for drugs that battle age-related diseases.

The medical data research company scored a $320 million investment from Regeneron Pharmaceuticals, Illumina and 17 U.S. health systems as it continues to build what is billed as the world’s largest genetic data base. The deal values privately held Truveta at more than $1 billion. The company aggregates medical records data from its partner institutions to link treatments with outcomes and other health information.

The San Francisco-based startup that develops cardiovascular drug treatments launched with $300 million Series A financing led by Arch Venture Partners, Perceptive Advisors and Sequoia Heritage. The company’s platform leverages a proprietary set of cardiac-specific tools that help analyze therapeutic candidates as well as patients’ individualized responses to treatment.

The health care data company that increasingly has been focused on artificial intelligence (AI) to support its value-based care programs announced a $275 million Series F funding round. The investment will fuel Innovaccer’s efforts to expand its collaboration with existing customers, introduce new AI and cloud capabilities, and scale a developer ecosystem on the platform. The company plans to add multiple co-pilots and agents to its offerings, including utilization management, prior authorization, clinical decision support, clinical documentation, care management and a contact center.